MOE-Tox Complete Profile

16 of the most common Mycotoxins produced by 5 Mycotoxin families Those Mycotoxins are:

Aflatoxins

• Aflatoxin B1
• Aflatoxin B2
• Aflatoxin G1
• Aflatoxin G2

Trichothecenes

• Stratoxin G
• Stratoxin H
• Isosatratoxin F
• Roridin A
• Roridin E
• Roridin H
• Roridin L-2
• Verrucarin J
• Verrucarin A

Other Mycotoxins

• Gliotoxin
• Ochratoxin A (OTA)
• Zearalenone (ZEA)

36 Organic Acids are analyzed to indicate key markers of metabolic health:

Glycolysis Metabolites

• Pyruvate
• Lactate

Citric Acid Cycle Metabolites

• Citrate
• Cis-Aconitate
• Isocitrate
• Alpha-Ketoglutarate
• Succinate
• Fumarate
• Malate

Fatty Acid Oxidation

• Adipate
• Suberate
• Ethylmalonate
• Methylsuccinate

Ketone Metabolites

• Beta-Hydroxybutyrate

Markers for Cofactor Need

• Alpha-Ketoisovalerate
• Alpha-Ketoisocaproate
• Alpha-Keto-Beta-Methylvalerate
• Beta-Hydroxyisovalerate
• Methylmalonate
• Kynurenate
• Hydroxymethylglutarate

Markers of Neurotransmitter Metabolism

• Vanilmandelate
• Homovanillate
• 5-Hydroxyindoleacetate
• Quinolinate

Markers of Detoxification

• Para-Hydroxyphenyllactate
• Orotate
• Alpha-Hydroxybutyrate
• Pyroglutamate
• Benzoate
• Hippurate

Markers of Bacterial Metabolism

• Para-Hydroxybenzoate
• Para-Hydroxyphenylacetate
• 2-Hydroxyphenylacetate
• 3-Indoleacetate
• Tricarballylate

14 metabolites are analyzed to assess exposure to 8 common environmental chemicals:

Xylene Exposure

• 3-Methylhippurate
• 2-Methylhippurate

Toluene Exposure

• Hippurate
• Benzoate

Benzene Exposure

• t,t-Muconic Acid

Trimethylbenzene Exposure

• 3,4-Dimethylhippurate

Styrene Exposure

• Mandelate
• Phenylglyoxylate
• Mandelate + Phenylglyoxylate

Phthalate Exposure

• Monoethyl Phthalate
• Phthalate
• Quinolinate

Paraben Exposure

• Para-Hydroxybenzoate

Methyl Tert-butyl Ether Exposure

• Alpha-Hydroxyisobutyrate

Testing Process

ELISA

The Mycotoxin Panel is run using Enzyme-Linked Immunosorbent Assay (ELISA).  An established immunological technique, ELISA is widely used to detect the presence of specific antibodies or antigens in a patient’s blood.

The ELISA method detects mycotoxins that have been structurally modified within the body providing more accurate results than similar testing run through mass spectrometry.

LC-MS/MS

Liquid Chromatography/ Triple Quadrupole Mass Spectrometry (LC-MS/MS) instrumentation is used to quantitatively evaluate patient urine specimens for metabolically-derived organic acids and evidence of exposure to environmental pollutants. Our Urinary Metabolic Profile is run on this comprehensive testing platform, which offers superb separation, resolution, and identification of compounds from a complex biological mixture such as urine, yielding precise and repeatable results.

More information on LC-MS/MS

Sample Report

Click To View The MOE-Tox Complete Sample Report

Specimen Requirements

The MOE-Tox Complete Profile requires a combination of liquid urine and dried urine samples which can be collected together as a single first morning void.

The specimen requirements are 1 dried urine card, and 3 ml of liquid urine. 

Click here for collection instructions